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创新团队
  • 畜产品安全与营养创新团队
研究方向

    耐药细菌与噬菌体的互作机制研究及噬菌体产品研发

代表性项目

    1.国家万人计划青年拔尖人才项目,动物源细菌重要耐药基因传播的控制策略研究,2024-01 / 2026-12,主持

    2.国家重点研发计划(子课题),耐药基因的宿主特异性及跨宿主/介质传播规律,2022-11 / 2025-12 ,主持

    3.JPIAMR国际合作项目,Novel interventions for eliminating one-health mobile antimicrobial resistance genes from human and animal microbiomes,2022-01 / 2024-12,主持

    4. 江苏省优秀青年基金,江苏省猪肉生产链tet(X4)阳性致病性大肠杆菌O157:H7的 产生机制及控制技术研究,2020-07 / 2023-06,主持

    5.江苏省自主创新项目,基于CRISPR/Cas9的猪肉源tet(X)变体基因传播阻断技术研究,2020-08 / 2022-07 ,主持

    6.农业部横向委托项目,生态环保优质动物源性肥料评价技术规范研制与试点,2020-01 / 2020-12,主持


代表性成果产出

    1. Tao He#; Ran Wang#; Dejun Liu#,et al.Emergence of plasmid-mediated high-level tigecycline resistance genes in animals and humans, Nature Microbiology, 2019, 4(9): 1450-1456.                                2. Tao He# ; Ruicheng Wei# ; Lili Zhang et al. Dissemination of the tet(X)-variant genes from layer farms to manure-receiving soil and corresponding lettuce, Environmental Science & Technology, 2021, 55(3): 1604-1614. 

    3. Tao He#, Jun Li#, Lan Gong, et al. Comprehensive analysis of antimicrobial, heavy metal and pesticide residues in commercial organic fertilizers and their correlation with tigecycline-resistant tet(X)-variant genes. Microbiology Spectrum. 2023,11(2):e0425122.  

    4. Tao He, Ruicheng Wei, Ruichao Li, et al.  Co-existence of tet(X4) and mcr-1 in two porcine Escherichia coli isolates. J Antimicrob Chemother 2020, 75(3): 764-766.                                                              5.Tao He, Ruichao Li, Ruicheng Wei, et al. Characterization of Acinetobacter indicus co-harbouring tet(X3) and blaNDM-1 of dairy cow origin. J Antimicrob Chemother 2020, 75: 2693-2696.