1.动物源细菌耐药性产生与传播机制

2.基于噬菌体的细菌耐药性防控策略研究

1. 国家自然科学基金青年科学基金项目，32102728，“外膜囊泡介导tet(X)变体基因及Tet(X)药物灭活酶水平转移机制研究”，2022/01-2024/12

2. 江苏省自然科学基金青年科学基金项目，BK20190261，“环丙沙星压力下胞内寄生猪鼻支原体耐药应答机制研究”，2019/07-2022/06

3. 江苏省农业科学院探索性颠覆性创新项目，ZX(21)1224，“基于T4SS靶向型合成噬菌体的细菌耐药性精准防控技术研究”，2021/07-2023/12

一、获得科技奖励

1. 神农中华农业科技奖优秀创新团队奖，“江苏省农业科学院动物支原体病防控创新团队”，2021.10，排名第13。

2. 首届江苏省畜牧兽医学会科技奖一等奖，“可转移替加环素耐药基因tet(X)变体的发现、传播机制与控制策略研究”，2021.11，排名第8。

3. 第四届江苏省农学会技术创新奖二等奖，“养殖业抗生素在养-种循环中污染风险及防控关键技术研究与应用”，2021.12，排名第11。

二、主要论文

1. Tao He*, Jun Li*, Lan Gong, Yang Wang, Ruichao Li, Xing Ji, Fengting Luan, Minmin Tang, Lei Zhu, Ruicheng Wei, Ran Wang. Comprehensive Analysis of Antimicrobial, Heavy Metal, and Pesticide Residues in Commercial Organic Fertilizers and Their Correlation with Tigecycline Resistant tet(X)-Variant Genes. Microbiology Spectrum. 2023, 11(2):e0425122.

2. Xingqi Tong*, Jun Li*, Ruicheng Wei, Lan Gong, Xing Ji, Tao He, Ran Wang. RW-BP100-4D, A Promising Antimicrobial Candidate with Broad-Spectrum Bactericidal Activity. Frontiers in Microbiology. 2022, 12:815980.

3. Jun Li, Yanna Wei, Jia Wang, Yao Li, Guoqing Shao, Zhixin Feng, Qiyan Xiong. Characterization of Mutations in DNA Gyrase and Topoisomerase IV in Field Strains and In Vitro Selected Quinolone-Resistant Mycoplasma hyorhinis Mutants. Antibiotics. 2022, 11:494.

4. Jun Li, Jia Wang, Jia Shao, Yao Li, Yanfei Yu, Guoqing Shao, Zhixin Feng, Qiyan Xiong. The Variable Lipoprotein Family Participates in the Interaction of Mycoplasma hyorhinis with Host Extracellular Matrix and Plasminogen. Veterinary Microbiology. 2022, 265:109310.

5. Jun Li*, Haihong Hao*, Menghong Dai, Heying Zhang, Jianan Ning, Guyue Cheng, Muhammad Abu Bakr Shabbir, Abdul Sajid, Zonghui Yuan. Resistance and Virulence Mechanisms of Escherichia coli Selected by Enrofloxacin in Chicken. Antimicrobial Agents and Chemotherapy. 2019, 63:e01824-18.

6.Jun Li, Heying Zhang, Jianan Ning, Abdul Sajid, Guyue Cheng, Zonghui Yuan, Haihong Hao. The Nature and Epidemiology of OqxAB, A Multidrug Efflux Pump. Antimicrobial Resistance and Infection Control. 2019, 8:44.